Project Scientist

Research Emphasis

My research involves developing computational approaches to studying biochemical networks. Applications of interest include:

• Elucidating the dynamic structure of metabolic networks
• The functional interpretation of the metabolome
• Impact of thermodynamics in biochemical network evolution
• Computational metabolic engineering
• Improved incorporation of fluxomic data into constraint-based models
• Understanding objective functions and constraints relevant to modeling mammalian and multi-cellular metabolism



2015, Ph.D. Bioengineering, University of California - San Diego, La Jolla, California

2008, B.S. Biomedical Engineering, University of Virginia, Charlottesville, Virginia

Select publications:

Zielinski, D.C. et. al., Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism., Scientific Reports 25;7:41241. (2017).

Zielinski, D.C. et. al., Pharmacogenomic and clinical data link non-pharmacokinetic metabolic dysregulation to drug side effect pathogenesis., Nature Communications 9;6:7101. (2015).

Google Scholar for full list of publications.

Contact Information

Email Address:

Mailing Address: 9500 Gilman Drive Mail Code 0412 La Jolla, CA 92093-0412