| Metabolic gene-deletion strains of Escherichia coli evolve to computationally predicted growth phenotypes. |
S. Fong; B.Ø. Palsson |
2004 |
| Uniform sampling of steady-state flux spaces: means to design experiments and to interpret enzymopathies. |
N.D. Price; J. Schellenberger; B.Ø. Palsson |
2004 |
| Using metabolic flux data to further constrain the metabolic solution space and predict internal flux patterns: the Escherichia coli spectrum. |
S.J. Wiback; R. Mahadevan; B.Ø. Palsson |
2004 |
| The evolution of molecular biology into systems biology. |
H.V. Westerhoff; B.Ø. Palsson |
2004 |
| In silico biotechnology. Era of reconstruction and interrogation. |
B.Ø. Palsson |
2004 |
| Genome-scale models of microbial cells: evaluating the consequences of constraints. |
N.D. Price; J.L. Reed; B.Ø. Palsson |
2004 |
| Reconstruction of microbial transcriptional regulatory networks. |
M.J. Herrgard; M.W. Covert; B.Ø. Palsson |
2004 |
| Hierarchical thinking in network biology: the unbiased modularization of biochemical networks. |
J.A. Papin; J.L. Reed; B.Ø. Palsson |
2004 |
| In Silico Metabolic Model and Protein Expression of Haemophilus influenzae Strain Rd KW20 in Rich Medium. |
A. Raghunathan; N.D. Price; M.Y. Galperin; K.S. Makarova; S. Purvine; A.F. Picone; T. Cherny; T. Xie; T.J. Reilly; R. Munson; R.E. Tyler; B.J. Akerley; A.L. Smith; B.Ø. Palsson; E. Kolker |
2004 |
| Integrating high-throughput and computational data elucidates bacterial networks. |
M.W. Covert; E.M. Knight; J.L. Reed; M.J. Herrgard; B.Ø. Palsson |
2004 |
| Monte Carlo sampling can be used to determine the size and shape of the steady-state flux space. |
S.J. Wiback; I. Famili; H.J. Greenberg; B.Ø. Palsson |
2004 |
| High-throughput mutation detection underlying adaptive evolution of Escherichia coli-K12. |
C. Honisch; A. Raghunathan; C.R. Cantor; B.Ø. Palsson; D. Boom |
2004 |
| Flagellar biosynthesis in silico: building quantitative models of regulatory networks. |
M.J. Herrgard; B.Ø. Palsson |
2004 |
| Reconstruction and validation of Saccharomyces cerevisiae iND750, a fully compartmentalized genome-scale metabolic model. |
N.C. Duarte; M.J. Herrgard; B.Ø. Palsson |
2004 |
| Reconstruction and functional characterization of the human mitochondrial metabolic network based on proteomic and biochemical data. |
T.D. Vo; H.J. Greenberg; B.Ø. Palsson |
2004 |
| The JAK-STAT signaling network in the human B-cell: an extreme signaling pathway analysis. |
J.A. Papin; B.Ø. Palsson |
2004 |
| Comparison of network-based pathway analysis methods. |
J.A. Papin; J. Stelling; N.D. Price; S. Klamt; S. Schuster; B.Ø. Palsson |
2004 |
| Network-based analysis of metabolic regulation in the human red blood cell. |
N.D. Price; J.L. Reed; J.A. Papin; S.J. Wiback; B.Ø. Palsson |
2003 |
| Constraints-based models: regulation of gene expression reduces the steady-state solution space. |
M.W. Covert; B.Ø. Palsson |
2003 |
| Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network. |
I. Famili; J. Forster; J. Nielsen; B.Ø. Palsson |
2003 |
| Genome-scale microbial in silico models: the constraints-based approach. |
N.D. Price; J.A. Papin; C.H. Schilling; B.Ø. Palsson |
2003 |
| Identifying constraints that govern cell behavior: a key to converting conceptual to computational models in biology? |
M.W. Covert; I. Famili; B.Ø. Palsson |
2003 |
| Thirteen years of building constraint-based in silico models of Escherichia coli. |
J.L. Reed; B.Ø. Palsson |
2003 |
| Development of network-based pathway definitions: the need to analyze real metabolic networks. |
B.Ø. Palsson; N.D. Price; J.A. Papin |
2003 |
| Quantitative analysis of Escherichia coli metabolic phenotypes within the context of phenotypic phase planes. |
R.U. Ibarra; P. Fu; B.Ø. Palsson; J.R. DiTonno; J.S. Edwards |
2003 |
| Metabolic pathways in the post-genome era. |
J.A. Papin; N.D. Price; S.J. Wiback; D.A. Fell; B.Ø. Palsson |
2003 |
| The convex basis of the left null space of the stoichiometric matrix leads to the definition of metabolically meaningful pools. |
I. Famili; B.Ø. Palsson |
2003 |
| Initial proteome analysis of model microorganism Haemophilus influenzae strain Rd KW20. |
E. Kolker; S. Purvine; M.Y. Galperin; S. Stolyar; D.R. Goodlett; A.I. Nesvizhskii; A. Keller; T. Xie; J.K. Eng; E. Yi; L. Hood; A.F. Picone; T. Cherny; B.C. Tjaden; A.F. Siegel; T.J. Reilly; K.S. Makarova; B.Ø. Palsson; A.L. Smith |
2003 |
| Scalable method to determine mutations that occur during adaptive evolution of Escherichia coli. |
A. Raghunathan; B.Ø. Palsson |
2003 |
| Systemic metabolic reactions are obtained by singular value decomposition of genome-scale stoichiometric matrices. |
I. Famili; B.Ø. Palsson |
2003 |