Publication Title Authors Publication Year Sort ascending
Enzyme promiscuity shapes adaptation to novel growth substrates

Guzmán GI, Sandberg TE, LaCroix RA, Nyerges Á, Papp H, de Raad M, King ZA,
Hefner Y, Northen TR, Notebaart RA, Pál C, Palsson BO, Papp B, Feist AM

2019
The genetic basis for adaptation of model-designed syntrophic co-cultures

Lloyd CJ, King ZA, Sandberg TE, Hefner Y, Olson CA, Phaneuf PV, O'Brien EJ, Sanders JG, Salido RA, Sanders K, Brennan C, Humphrey G, Knight R, Feist AM

2019
Cross-compartment metabolic coupling enables flexible photoprotective mechanisms in the diatom Phaeodactylum tricornutum

Broddrick JT, Du N, Smith SR, Tsuji Y, Jallet D, Ware MA, Peers G, Matsuda Y, 
Dupont CL, Mitchell BG, Palsson BO, Allen AE

2019
Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom

Smith SR, Dupont CL, McCarthy JK, Broddrick JT, Oborník M, Horák A, Füssy Z, Cihlář J, Kleessen S, Zheng H, McCrow JP, Hixson KK, Araújo WL, Nunes-Nesi A, Fernie A, Nikoloski Z, Palsson BO, Allen AE

2019
Adaptive laboratory evolution of a genome-reduced Escherichia coli

D. Choe; J.Hyoung Lee; M. Yoo; S. Hwang; B.Hyun Sung; S. Cho; B. Palsson; S.Chang Kim; B.K. Cho

2019
A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action

Yang, J.H., Wright, S.N., Hamblin, M., McCloskey, D., Alcantar, M.A., Schrubbers, L., Lopatkin, A.J., Satish, S., Nili, A., Palsson, B.O., Walker, G.C., Collins, J.J

2019
Adaptive laboratory evolution of Escherichia coli under acid stress

Du B, Olson CA, Sastry AV, Fang X, Phaneuf PV, Chen K, Wu M, Szubin R, Xu S, Hefner Y, Feist AM, Palsson BO

2019
Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0.

L. Heirendt; S. Arreckx; T. Pfau; S.N. Mendoza; A. Richelle; A. Heinken; H.S. Haraldsdóttir; J. Wachowiak; S.M. Keating; V. Vlasov; S. Magnusdóttir; C.Yu Ng; G. Preciat; A. Žagare; S.H.J. Chan; M.K. Aurich; C.M. Clancy; J. Modamio; J.T. Sauls; A. Noronha; A. Bordbar; B. Cousins; D.C.El Assal; L.V. Valcarcel; I. Apaolaza; S. Ghaderi; M. Ahookhosh; M. Ben Guebila; A. Kostromins; N. Sompairac; H.M. Le; D. Ma; Y. Sun; L. Wang; J.T. Yurkovich; M.A.P. Oliveira; P.T. Vuong; L.P.El Assal; I. Kuperstein; A. Zinovyev; S. Hinton; W.A. Bryant; F.J.Aragón Artacho; F.J. Planes; E. Stalidzans; A. Maass; S. Vempala; M. Hucka; M.A. Saunders; C.D. Maranas; N.E. Lewis; T. Sauter; B.Ø. Palsson; I. Thiele; R.M.T. Fleming

2019
Characterization of CA-MRSA TCH1516 exposed to nafcillin in bacteriological and physiological media

Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon
N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Pogliano J, Knight R,
Nizet V, Palsson BO, Feist AM

2019
OxyR is a convergent target for mutations acquired during adaptation to oxidative stress-prone metabolic states

Anand A, Chen K, Catoiu E, Sastry AV, Olson CA, Sandberg TE, Seif Y, Xu S, Szubin R, Yang L, Feist AM, Palsson BO

2019
BOFdata: Generating biomass objective functions for genome-scale metabolic models from experimental data

Lachance JC, Lloyd CJ, Monk JM, Yang L, Sastry AV, Seif Y, Palsson BO,
Rodrigue S, Feist AM, King ZA, Jacques PÉ

2019
High-quality genome-scale metabolic modeling of Pseudomonas putida highlights its broad metabolic capabilities

Nogales J, Mueller J, Gudmundsson S, Canalejo FJ, Duque E, Monk J, Feist AM, Ramos JL, Niu W, Palsson BO

2019
Primary transcriptome and translatome analysis determines transcriptional and translational regulatory elements encoded in the Streptomyces clavuligerus genome

Hwang S, Lee N, Jeong Y, Lee Y, Kim W, Cho S, Palsson BO, Cho BK

2019
Adaptive evolution reveals a tradeoff between growth rate and oxidative stress during naphthoquinone-based aerobic respiration

Anand A, Chen K, Yang L, Sastry AV, Olson CA, Poudel S, Seif Y, Hefner Y, Phaneuf PV, Xu S, Szubin R, Feist AM, Palsson BO

2019
The y-ome defines the 35% of Escherichia coli genes that lack experimental evidence of function

S. Ghatak; Z.A. King; A. Sastry; B.O. Palsson

2019
Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism

Cheng C, O'Brien EJ, McCloskey D, Utrilla J, Olson C, LaCroix RA, Sandberg TE, Feist AM, Palsson BO, King ZA

2019
Expanding the uses of genome‐scale models with protein structures

Mih N and Palsson BO

2019
Escher-FBA: a web application for interactive flux balance analysis

E. Rowe; B.O. Palsson; Z.A. King

2018
High-Level dCas9 Expression Induces Abnormal Cell Morphology in Escherichia coli.

S. Cho; D. Choe; E. Lee; S.Chang Kim; B. Palsson; B.K. Cho

2018
Basics of genome-scale metabolic modeling and applications on C1-utilization.

I. Kabimoldayev; A.Duc Nguyen; L. Yang; S. Park; E.Yeol Lee; D. Kim

2018
iCN718, an Updated and Improved Genome-Scale Metabolic Network Reconstruction of Acinetobacter baumannii AYE

C.J. Norsigian; E. Kavvas; Y. Seif; B.O. Palsson; J.M. Monk

2018
Reframing gene essentiality in terms of adaptive flexibility.

G.I. Guzman; C.A. Olson; Y. Hefner; P.V. Phaneuf; E. Catoiu; L.B. Crepaldi; L.Goldschmid Micas; B.O. Palsson; A.M. Feist

2018
Genome-scale metabolic reconstructions of multiple Salmonella strains reveal serovar-specific metabolic traits.

Y. Seif; E. Kavvas; J.C. Lachance; J.T. Yurkovich; S.P. Nuccio; X. Fang; E. Catoiu; M. Raffatellu; B.O. Palsson; J.M. Monk

2018
Laboratory evolution reveals regulatory and metabolic trade-offs of glycerol utilization in Saccharomyces cerevisiae.

T. Strucko; K. Zirngibl; F. Pereira; E. Kafkia; E.T. Mohamed; M. Rettel; F. Stein; A.M. Feist; P. Jouhten; K.Raosaheb Patil; J. Forster

2018
ALEdb 1.0: a database of mutations from adaptive laboratory evolution experimentation.

P.V. Phaneuf; D. Gosting; B.O. Palsson; A.M. Feist

2018
Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Systems biology as an emerging paradigm in transfusion medicine.

J.T. Yurkovich; A. Bordbar; O.E. Sigurjónsson; B.O. Palsson

2018
Modeling genome-wide enzyme evolution predicts strong epistasis underlying catalytic turnover rates

D. Heckmann; D.C. Zielinski; B.O. Palsson

2018
Multiple optimal phenotypes overcome redox and glycolytic intermediate metabolite imbalances in knockout evolutions.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions.

E.S. Kavvas; Y. Seif; J.T. Yurkovich; C. Norsigian; S. Poudel; W.W. Greenwald; S. Ghatak; B.O. Palsson; J.M. Monk

2018