Publication Title Authors Publication Year Sort ascending
Synthetic Biology Tools for Novel Secondary Metabolite Discovery in Streptomyces

Lee N, Hwang S, Lee Y, Cho S, Palsson B, Cho BK

2019
The Escherichia coli transcriptome mostly consists of independently regulated modules

Sastry AV, Gao Y, Szubin R, Hefner Y, Xu S, Kim D, Choudhary KS, Yang L, King ZA, Palsson BO

2019
Pseudogene repair driven by selection pressure applied in experimental evolution.

A. Anand; C.A. Olson; L. Yang; A.V. Sastry; E. Catoiu; K.Sonal Choudhary; P.V. Phaneuf; T.E. Sandberg; S. Xu; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2019
Cellular responses to reactive oxygen species are predicted from molecular mechanisms

Yang L, Mih N, Anand A, Park JH, Tan J, Yurkovich JT, Monk JM, Lloyd CJ,
Sandberg TE, Seo SW, Kim D, Sastry AV, Phaneuf P, Gao Y, Broddrick JT, Chen K,
Heckmann D, Szubin R, Hefner Y, Feist AM, Palsson BO.

2019
Genome-scale model of metabolism and gene expression provides a multi-scale description of acid stress responses in Escherichia coli

Du B, Yang L, Lloyd CJ, Fang X, Palsson BO

2019
A computational knowledge-base elucidates the response of Staphylococcus aureus to different media types.

Y. Seif; J.M. Monk; N. Mih; H. Tsunemoto; S. Poudel; C. Zuniga; J. Broddrick; K. Zengler; B.O. Palsson

2019
Metabolic Systems Analysis of Shock-Induced Endotheliopathy (SHINE) in Trauma: A New Research Paradigm

Henriksen HH, McGarrity S, SigurÐardóttir RS, Nemkov T, D'Alessandro A, Palsson BO, Stensballe J, Wade CE, Rolfsson Ó, Johansson PI

2019
BiGG Models 2020: multi-strain genome-scale models and expansion across the phylogenetic tree

Norsigian CJ, Pusarla N, McConn JL, Yurkovich JT, Dräger A, Palsson BO, King Z

2019
ALEdb 1.0: a database of mutations from adaptive laboratory evolution experimentation.

P.V. Phaneuf; D. Gosting; B.O. Palsson; A.M. Feist

2018
Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Systems biology as an emerging paradigm in transfusion medicine.

J.T. Yurkovich; A. Bordbar; O.E. Sigurjónsson; B.O. Palsson

2018
Modeling genome-wide enzyme evolution predicts strong epistasis underlying catalytic turnover rates

D. Heckmann; D.C. Zielinski; B.O. Palsson

2018
Multiple optimal phenotypes overcome redox and glycolytic intermediate metabolite imbalances in knockout evolutions.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions.

E.S. Kavvas; Y. Seif; J.T. Yurkovich; C. Norsigian; S. Poudel; W.W. Greenwald; S. Ghatak; B.O. Palsson; J.M. Monk

2018
Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models

D. Heckmann; C.J. Lloyd; N. Mih; Y. Ha; D.C. Zielinski; Z.B. Haiman; A.Amer Desouki; M.J. Lercher; B.O. Palsson

2018
Systematic discovery of uncharacterized transcription factors in Escherichia coli K-12 MG1655.

Y. Gao; J.T. Yurkovich; S.Woo Seo; I. Kabimoldayev; A. Dräger; K. Chen; A.V. Sastry; X. Fang; N. Mih; L. Yang; J. Eichner; B.K. Cho; D. Kim; B.O. Palsson

2018
Recon3D enables a three-dimensional view of gene variation in human metabolism.

E. Brunk; S. Sahoo; D.C. Zielinski; A. Altunkaya; A. Dräger; N. Mih; F. Gatto; A. Nilsson; G.Andres Pre Gonzalez; M.Kathrin Aurich; A. Prlić; A. Sastry; A.D. Danielsdottir; A. Heinken; A. Noronha; P.W. Rose; S.K. Burley; R.M.T. Fleming; J. Nielsen; I. Thiele; B.O. Palsson

2018
Gapless, Unambiguous Genome Sequence for Escherichia coli C, a Workhorse of Industrial Biology

J.E. Pekar; P. Phaneuf; R. Szubin; B. Palsson; A. Feist; J.M. Monk

2018
Network-level allosteric effects are elucidated by detailing how ligand-binding events modulate utilization of catalytic potentials.

J.T. Yurkovich; M.A. Alcantar; Z.B. Haiman; B.O. Palsson

2018
ssbio: A Python Framework for Structural Systems Biology

N. Mih; E. Brunk; K. Chen; E. Catoiu; A. Sastry; E. Kavvas; J.M. Monk; Z. Zhang; B.O. Palsson

2018
Predicting the metabolic capabilities of Synechococcus elongatus PCC 7942 adapted to different light regimes.

J.T. Broddrick; D.G. Welkie; D. Jallet; S.S. Golden; G. Peers; B.O. Palsson

2018
A unified resource for transcriptional regulation in Escherichia coli K-12 incorporating high-throughput-generated binding data into RegulonDB version 10.0

A. Santos-Zavaleta; M. Sánchez-Pérez; H. Salgado; D.A. Vázquez-Ramírez; S. Gama-Castro; V.H. Tierrafría; S.J.W. Busby; P. Aquino; X. Fang; B.O. Palsson; J.E. Galagan; J. Collado-Vides

2018
Systems assessment of transcriptional regulation on central carbon metabolism by Cra and CRP.

D. Kim; S.Woo Seo; Y. Gao; H. Nam; G.I. Guzman; B.K. Cho; B.O. Palsson

2018
Sugar-stimulated CO2 sequestration by the green microalga Chlorella vulgaris

W. Fu; S. Gudmundsson; K. Wichuk; S. Palsson; B.O. Palsson; K. Salehi-Ashtiani; ður ólfsson

2018
Growth Adaptation of gnd and sdhCB Escherichia coli Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance.

D. Choe; R. Szubin; S. Dahesh; S. Cho; V. Nizet; B. Palsson; B.K. Cho

2018
Metagenomics-Based, Strain-Level Analysis of Escherichia coli From a Time-Series of Microbiome Samples From a Crohn's Disease Patient

X. Fang; J.M. Monk; S. Nurk; M. Akseshina; Q. Zhu; C. Gemmell; C. Gianetto-Hill; N. Leung; R. Szubin; J. Sanders; P.L. Beck; W. Li; W.J. Sandborn; S.D. Gray-Owen; R. Knight; E. Allen-Vercoe; B.O. Palsson; L. Smarr

2018
COBRAme: A computational framework for genome-scale models of metabolism and gene expression.

C.J. Lloyd; A. Ebrahim; L. Yang; Z.A. King; E. Catoiu; E.J. O'Brien; J.K. Liu; B.O. Palsson

2018
Quantitative -omic data empowers bottom-up systems biology

J.T. Yurkovich; B.O. Palsson

2018
Estimating Metabolic Equilibrium Constants: Progress and Future Challenges

B. Du; D.C. Zielinski; B.O. Palsson

2018